Live Animal Resources
Rat CLAMS unit
The Rat Comprehensive Lab Animal Monitoring System (CLAMS) unit is housed in the Department of Laboratory Animal Resources (DLAR).
Use of the CLAMS provides researchers with a comprehensive platform for monitoring metabolic and physiological parameters. Users can monitor oxygen and carbon dioxide concentrations by volume at the inlet and outlet ports of a chamber, canopy, tent, or mask through which a known flow of air is being forcibly ventilated. In addition to gas exchange analysis, the system offers a complete solution for studying metabolic activity and physiological responses.
The CLAMS accommodates 24 single housed animals.
Located in the Department of Lab Animal Resources (DLAR), an AAALAC International accredited facility.
The DLAR also houses a mouse CLAMS system.听 For information on the mouse unit please contact Dr. Beata Lecka-Czernik, Beata.LeckaCzernik@utoledo.edu or 419-383-4140
For information on the Rat CLAMS unit click here to be directed to the DLAR page.
To inquire about reserving the CLAMS unit and for training please contact Dr. Andrea Kalinoski
IVIS Spectrum
The IVIS Spectrum () is a whole animal fluorescence imaging system. The IVIS Spectrum is a multimodal bioluminescent and fluorescent imaging system specifically designed for noninvasive longitudinal imaging of cells and tissues in small animals. This instrument facilitates the study of biological processes via fluorescence in small animals, including tumor growth, cancer metastasis, bacterial infections, immune responses and inflammation, and regulation of tissue-specific gene expression.听听
Contact Dr. Andrea Kalinoski for training and more information.听 听
ACUSION Sequoia C512
ACUSON Sequoia C512 Echocardiography system is a valuable tool for studying cardiovascular disease processes in small animals, including ischemic heart disease, heart failure, cardiac hypertrophy and remodeling, hypertension and diabetic cardiomyopathy.听 Capabilities include high-resolution imaging, tissue harmonic imaging, differential echo amplification, spectral Doppler (pulsed and continuous wave), color Doppler (for measurements of velocity energy and tissue Doppler imaging) and color-Doppler M-mode imaging.听
Contact Dr. Andrea Kalinoski for more information.
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TCS SP5 Laser Scanning Confocal Microscope with MP
This system is capable of collecting up to five colors simultaneously for quantitative confocal image analysis in both live cell and animal imaging, fixed tissue and includes the capabilities for 3-D reconstruction, FRAP, FRET, animation, stereo imaging, single layer projection, time lapse collection, and co-localization analysis.
Contact Dr. Andrea Kalinoski for more information.